The Institute for Protein Design is looking for talented individuals to join its growing team. Persons who enjoy working in a dynamic team environment should contact us to learn more about potential job opportunities.


Baker Lab: Lab Manager

Baker Lab: Lab Manager

The lab manager will fulfill their duties in the Baker lab, assisting about 50 +/- members that include postdocs, grad students, undergrads, volunteers, and visiting scholars.

Opening: Immediate


The Baker Laboratory at the University of Washington’s Department of Biochemistry, Institute for Protein Design currently has an outstanding opportunity for a Research Scientist/Engineer 2 to serve as Laboratory Manger.

This individual will serve as Laboratory Manager for a 50 –person laboratory of postdoctoral fellows, graduate students and undergraduate student helpers. This person will manage the Baker Laboratory scientific supply inventory and ordering, and assist in monitoring laboratory usage and equipment maintenance, and oversee the work of the undergraduate support aids, with assigned duty support from Baker laboratory postdoctoral fellows and graduate students.  This role also involves managing undergraduates who support the lab in glassware washing and standard solution preparation. This role also involves orientation of new lab members, providing educational information on lab practice, professional conduct and chemical safety. Strong organizational, leadership and communication skills are required.


  • Communicates with David Baker (and IPD staff) on the status of action items that are being accomplished on a weekly basis. Works with post-docs and graduate students appointed by both the Lab Manager and David Baker to discuss efficiently ways to meet weekly goals.
  • Maintains laboratory supply inventory by checking stock to determine inventory level; anticipating needed supplies; placing and expediting orders for supplies; verifying receipt of supplies including
    delivery of packing slips to Biochemistry offices. Negotiates with vendors to purchase bulk quantities of supplies with price discounts. Collaborates with IPD staff to initiate standing order purchases of bulk supplies for efficiency.
  • Organize lab layout and supplies to increase efficiency of use for lab members. Includes unpacking supplies and sorting into appropriate storage and arranging for undergraduate students and other lab
    members to monitor inventory levels and efficiency
  • Arranging small equipment replacement, service, and repair. Arrange service contracts on new equipment and renew annually. Tag new equipment and handle equipment inventory.
  • Orient new lab members and provide educational information about efficient laboratory usage and safety procedures that must be followed. Appoints lab members to help monitor lab usage and ensure that safety procedures are followed.
  • Assists in training new users in proper use of basic laboratory facilities and equipment. Appoints lab members to train other users in specialized lab equipment.
  • Assist in managing Chemical Inventory on MyChem; and utilizing in-lab chemical stock lists before order more. Ensuring that researching post-docs and grad- students are educated about MyChem and basic chemical safety before ordering chemicals for their research.
  • Trains lab users on sharps management, biohazard and chemical waste disposal.  Monitors, with the help of appointed post-docs and grad students, users for overall lab cleanliness. Determines if cleanliness is met, and reward lab members as the Lab manager sees fit.
  • Attend Laboratory Safety/ Building safety quarter meetings, and relay information to Baker Lab members; Act as a lab safety evacuation warden and train and assist Lab members in evacuation safety and strategy
  • Attend quarterly HHMI fiscal meetings and relay pertinent information to Baker Lab members.
  • In collaboration with Biochemistry department human resources; manage advertisement, hiring, training and supervision of undergraduate student helpers, and firing and coordinate with UW temporary services to secure temporary help in the absence of undergraduate support (e.g. student exam / break times).
  • Manage and maintain common stock solutions and supplies with the assistance of undergrad student
    helpers. Trains undergraduate helpers in the proper procedures of buffer preparation, etc.; responsible for the final QC of stocks before release to the lab.
  • Manage laboratory gene sequencing purchase orders and vendor web site systems for associating ordering scientists with defined purchase orders.
  • Genewiz Sequencing
  • Integrated DNA Technologies
  • Custom Array
  • Arrange pipette calibration and repair when requested by lab members or as necessary.
  • May assist in setting up repair or maintenance service calls for large equipment.
  • Assist in managing the archival of plasmids stocks, cell stocks, etc. of leaving lab members. Archival of laboratory notebooks is not required. 
  • Work with Program Operations to ensure that the lab is operating smoothly, or when any assistance or back-up is needed. Refer to Ops for any lab protocols outside of the wet lab, and communicate any issues or concerns.
  • BS in Biochemistry or related field
  • 2 years experience working in a laboratory setting
  • Strong organizational abilities
  • Demonstrated ability to work efficiently and independently
  • Ability to pay attention to procedural details
  • Ability to keep meticulous records
  • Ability to multi-task, prioritize multiple ongoing projects, anticipate the need for assistance and
    seek it proactively
  • Must have good communication skills.
  • Must be able to lift and move 40 pounds.
  • Experience using specialized research equipment
  • 1-2 years prior research laboratory experience
  • Mechanically inclined, willing to learn about various large instruments
  • Prior experience managing people

    Application Process:
    The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process.  These assessments may include Work Authorization, Criminal Conviction History, Cover Letter and/or others.  Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page.  If you select to take it later, it will appear on your “My Jobs” page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
Condition of Employment:
  • Lab Manager’s regular work hours, Monday to Friday (~8 hours per day).  If the Lab Manager must
    request time off, the Lab Manager must notify David Baker (or his designated proxy) via email.
  • If the Lab Manager intends to work outside regular hours, or overtime hours to complete regular
    Lab manager duties (in excess of 40 hours/week), approval must be acquired by e-mail from David Baker (or his designated proxy). Ideally, notification should be provided prior to work; however, it is understood that work can arise last minute and that notification should be provided ASAP.
  • While on vacation, the Lab Manager will have pre-arranged with David Baker and appointed post-docs and graduate students for how the Lab Manager duties will be achieved while the Lab Manager out.

    Appointment of the successful candidate to this position may be made contingent upon a satisfactory outcome of a criminal conviction history check .

Click to apply

Gu Lab: Postdoctoral Fellow

Gu Lab: Postdoctoral Fellow

Postdoctoral positions in protein barcoding and in situ DNA sequencing technologies for protein design at the University of Washington

Openings: Closed. Please check back at a later time. 


The laboratory of Dr. Liangcai Gu in the Department of Biochemistry and the Institute for Protein Design (IPD) at the University of Washington School of Medicine invites applications for up to three postdoctoral positions in image processing for in situ polony sequencing, next-generation sequencing for immune profiling, and protein barcoding technologies. The positions are available immediately.

We use quantitative protein interaction profiling to understand molecular recognition and guide computational protein design. To fundamentally improve quality and cost-effectiveness of high-throughput protein analysis, we develop protein interaction sequencing technologies by coupling ‘protein barcoding’ techniques to in situ barcode (or polony) sequencing, a powerful extension of next-generation sequencing technologies. Proteins are barcoded by attaching them to a barcoding DNA via enzymatic conjugation or protein displays. In situ polony sequencing can directly measure protein interactions in massively parallel at a single-molecule or single-cell level. An example of protein interaction sequencing is a single-molecular-interaction sequencing (SMI-seq) technology we recently developed (Nature, 2014, 515, 554–557) for ‘library-by-library’ or ‘all-by-all’ interaction profiling. We apply SMI-seq and others to measure natural or synthetic protein interactions to explore the druggability of human protein interactomes and to develop molecule sensors, vaccines and therapeutic T cells. We collaborate with world-class laboratories on protein design and sequencing technologies at the University of Washington and other institutes. Postdocs will work in a highly interdisciplinary and collaborative research environment and can be under a joint supervision of Dr. Gu and another advisor(s) with complementary expertise and research interests. Postdocs jointly trained in IPD and any Seattle-area research institute (including the University of Washington) are also eligible to apply for a Washington Research Foundation (WRF)‒IPD Innovation Fellowship (http://www.ipd.uw.edu/fellows/).


Applicants should have a Ph.D. degree (or equivalent) in related fields including, but not limited to biochemistry, bioengineering, bioinformatics, biophysics, computer science and chemistry. Highly desirable backgrounds/skills include i) phage, ribosome, mRNA or other protein display techniques for protein engineering; ii) high-throughput image processing and analysis; iii) next-generation sequencing of immune repertoire; iv) strong programming skills in scripting language (Python or Perl), statistical and computing language (R or MATLAB), and/or programing language (C/C++ /Java).

Applicants should have a strong publication record, good spoken and written communication skills. Interested applicants should send i) a cover letter briefly describing your previous experience and your future research interests/plans, ii) a curriculum vitae, and iii) contact information of three references to Dr. Liangcai Gu (gulab1@uw.edu).

The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.


Please apply through one of the sites below:

Nature Jobs

Science Careers