• Frontiers of Knowledge Award goes to David Baker, Demis Hassabis and John Jumper

    Frontiers of Knowledge Award goes to David Baker, Demis Hassabis and John Jumper

    The 15th BBVA Foundation Frontiers of Knowledge Award in Biology and Biomedicine has gone to David Baker, Demis Hassabis and John Jumper “for their contributions to the use of artificial intelligence for the accurate prediction of the three-dimensional structure of proteins.” From the BBVA Foundation: Baker – a Professor of Biochemistry at the University of […]

  • Establishing our first international translational research project

    Establishing our first international translational research project

    From our partners at the BioInnovation Institute: BioInnovation Institute (BII), an international enterprise foundation with a non-profit objective incubating and accelerating world-class life science research, announces today that it has accepted a new project into its Bio Studio program. Based on recent breakthroughs in Artificial Intelligence (AI) and protein design, the project is creating a […]

  • David Baker to present at the NIH Director’s Lecture Series

    David Baker to present at the NIH Director’s Lecture Series

    David Baker presented at the NIH Director’s Wednesday Afternoon Lecture Series on December 14, 2022. From the National Institutes of Health: The NIH Director’s Wednesday Afternoon Lecture Series, colloquially known as WALS, is the highest-profile lecture program at the NIH. Traditionally, lectures have occurred on most Wednesdays from September through June from 3:00 to 4:00 […]

  • A diffusion model for protein design

    A diffusion model for protein design

    A team led by Baker Lab scientists Joseph Watson, David Juergens, Nate Bennett, Brian Trippe, and Jason Yim has created a powerful new way to design proteins by combining structure prediction networks and generative diffusion models. The team demonstrated extremely high computational success and tested hundreds of A.I.-generated proteins in the lab, finding that many […]

  • ProteinMPNN excels at creating new proteins

    ProteinMPNN excels at creating new proteins

    Over the past two years, machine learning has revolutionized protein structure prediction. Now, three papers in Science describe a similar revolution in protein design. In the new papers, scientists in the Baker lab show that machine learning can be used to create proteins much more accurately and quickly than previously possible. This could lead to […]

  • Design of membrane-traversing peptides leads to new spinout

    Design of membrane-traversing peptides leads to new spinout

    Researchers at the Institute for Protein Design have discovered how to create peptides that slip through membranes and enter cells. This drug design breakthrough may lead to new medications for a wide variety of health disorders, including cancer, infection, and inflammation. This research appears in the journal Cell [PDF]. “This new ability to design membrane-permeable […]

  • Annual Report 2022

    Annual Report 2022

    [foogallery id=”6921″] Protein design reached two major milestones this year: Our Institute succeeded in producing its first fully-approved medicine, and our spinout companies have together raised over one billion dollars in capital. We are pleased to present this overview of the progress made at the Institute for Protein Design during the past year. 2022 Annual […]

  • Biosensor startup Monod secures $25M seed financing

    Biosensor startup Monod secures $25M seed financing

    Monod Bio, a life sciences company developing custom diagnostic biosensors that emit light to detect specific biomolecules of interest, today announced it has raised a $25M seed financing round. The round was led by Matrix Capital, with participation from the Global Health Investment Corporation, Cercano Management, The Washington Research Foundation, Boom Capital Ventures, Sahsen Ventures, […]

  • Celebrating our 10-year Anniversary

    Celebrating our 10-year Anniversary

    [foogallery id=”6856″]   This week we celebrated the 10-year anniversary of the Institute for Protein Design. Current members, advisors, supporters, and old friends all came together on campus to share memories and forge new friendships. It was a night to remember. A lot has changed in the past decade. At our founding, the concept of […]

  • Training A.I. to generate medicines and vaccines

    Training A.I. to generate medicines and vaccines

    Today we report in Science [PDF] the development of artificial intelligence software that can create proteins that may be useful as vaccines, cancer treatments, or even tools for pulling carbon pollution out of the air. This project was led by Jue Wang, Doug Tischer, and Joseph L. Watson, who are postdoctoral scholars at UW Medicine, […]