We aim to design a new world of proteins to address 21st century challenges in medicine, energy, and technology.





  • Potent anti-cancer proteins with fewer side effects
    Jan 9. 2019: New publication on the design of potent anti-cancer proteins
  • New designer proteins mimic DNA
    Dec. 28, 2018: New publication in Nature from the Baker Lab!
  • Fluorescent proteins designed from scratch
    Sep. 12, 2018: Check out the latest publication in Nature from the Baker lab!
  • 2018 IPD Newsletter from David Baker
    Jul. 23, 2018: Read about what happened in the last year at the IPD!
  • Alfatoxin project update
    Jul. 16, 2018: Check out the latest video from the Foldit alfatoxin project!
  • Open Philanthropy Project Award
    Apr. 4, 2018: The Institute for Protein Design at UW Medicine in Seattle has been awarded $11.3 million from the Open Philanthropy Project! Graphic by Possu Huang.
  • The 32nd Annual Symposium of The Protein Society
    Mar. 16, 2018: Congratulations to Dr. Baker on winning the Hans Neurath award from the Protein Society!
  • De Novo Design of Membrane Proteins
    Mar. 1, 2018: It is now possible to create complex, custom-designed transmembrane proteins from scratch!

 Research Spotlight

Two-Component Icosahedra

A paper recently published in Science titled “Accurate design of megadalton-scale multi-component icosahedral protein complexes,” introduces us to the ability to design two-component icosahedra. A former Baker lab member, Jacob Bale, is the first author on the paper.

Read more…

Beyond the Institute

From Research Into Company

PvP Biologics is the latest spin-out from IPD, and although a young company, they’ve already announced a $35M agreement with Takeda. Their enzyme, KumaMax, looks to help those with Celiac disease. Keep an eye on them as they continue their research!

Read more…


Citizen Scientists

We know that computers are smart, but they can sometimes miss important things because of the way they are programmed. The same goes for researchers! This is where Foldit comes in: everyday people can play and help us discover better protein designs through their unique creativity and ingenuity.

Get started!