Institute for Protein Design

What is Protein Design?

Check out our Infograph on Protein Design !  Watch this in depth discussion on protein design by Prof. David Baker, the Head of the IPD !

Proteins are the workhorses of the cell, carrying out the essential functions of life.  The function that a given protein carries out, such as catalyzing a chemical reaction to generate energy, is dependent on the three-dimensional structure of the protein.

Given the increased understanding in the mechanisms and rules that govern protein structures, scientists at the IPD have translated these rules into a computer program, Rosetta, that allows for the modeling of protein structures as well as the design of novel proteins with novel functions.

As most protein structures and functions of naturally occurring proteins have evolved by facing the challenges of millions of years of evolution, protein design opens the door to the design of new proteins to face 21st century challenges in medicine, energy and technology.


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