We aim to design a new world of proteins to address 21st century challenges in medicine, energy, and technology.

  • The 32nd Annual Symposium of The Protein Society
    Mar. 16, 2018: Congratulations to Dr. Baker on winning the Hans Neurath award from the Protein Society!
  • De Novo Design of Membrane Proteins
    Mar. 1, 2018: It is now possible to create complex, custom-designed transmembrane proteins from scratch!
  • UW Medicine David Baker
    Feb 22, 2018: Listen to a recent interview David had with KJZZ 91.5!
  • Graphic: John Hersey / New York Times
    End-of-year profile in the New York Times
  • Computationally Designed Synthetic Nucleocapsid
    Computationally Designed Synthetic Nucleocapsid
  • Programmimg peptide design
    A New World of Designed Macrocycles
  • IPD_Flu_MiniBinder
    Massively parallel de novo protein design for targeted therapeutics
  • Massive Parallel Protein Design
    Massively parallel de novo protein design, synthesis and testing (illustration by Gabe Rocklin)
  • Science Cover
    Computational design of two-component icosahedral protein nanocages
  • fluglue_IPD_posting
    Design Process for Flu-Glue, a Potent Computationally Deigned Anti-Flu Protein.
  • benbasanta-ntf2-1-10-17
    De novo designed pocket proteins
  • Prot_struct_metaGenome
    Protein Structure Determination from Metagenomic Sequence.
  • David_Baker2
    David Baker, Ph.D. Professor of Biochemistry, Director of the Institute for Protein Design
 Research Spotlight

Two-Component Icosahedra

A paper recently published in Science titled “Accurate design of megadalton-scale multi-component icosahedral protein complexes,” introduces us to the ability to design two-component icosahedra. A former Baker lab member, Jacob Bale, is the first author on the paper.

Read more…

Beyond the Institute

From Research Into Company

PvP Biologics is the latest spin-out from IPD, and although a young company, they’ve already announced a $35M agreement with Takeda. Their enzyme, KumaMax, looks to help those with Celiac disease. Keep an eye on them as they continue their research!

Read more…


Citizen Scientists

We know that computers are smart, but they can sometimes miss important things because of the way they are programmed. The same goes for researchers! This is where Foldit comes in: everyday people can play and help us discover better protein designs through their unique creativity and ingenuity.

Get started!