David Baker, PhD

Professor, Department of Biochemistry

David is the Director of the Institute for Protein Design, a Howard Hughes Medical Institute Investigator, professor in biochemistry, and an adjunct professor of genome sciences, bioengineering, chemical engineering, computer science, and physics at the University of Washington. The Baker Lab is focused on the design of macromolecular structures and functions.

Gaurav Bhardwaj, PhD

Assistant Professor, Department of Medicinal Chemistry

The Bhardwaj Lab is developing computational and experimental tools for high-throughput design of peptide-based therapeutics. We aim to develop a general rulebook of design principles for the custom design of peptides with enhanced membrane permeability, oral bioavailability, and blood-brain barrier traversal. We focus on designing peptides against a broad range of disease-related molecular targets, including validated targets in antibiotic resistance, chronic pain, and neurodegenerative disorders.

Frank DiMaio, PhD

Associate Professor, Department of Biochemistry

The DiMaio Lab is focused on protein structure determination from sparse and noisy experimental data. Improvements to structure prediction – both sampling methods and forcefields – are critical to designing proteins with novel functions.

Neil King, PhD

Assistant Professor, Department of Biochemistry

The King Lab is designing protein nanomaterials with the goal of creating new opportunities for the treatment of disease. Working with collaborators around the world, they are establishing a design-build-test cycle to use feedback from functional assays in vitro and in vivo to optimize the performance of the designed materials.

Sanjay Srivatsan, PhD

Assistant Professor, Fred Hutch

IPD Affiliate Lab

The Srivatsan Lab is developing novel sequence-based technologies that enable scientists to examine relationships between molecules and trace cellular dynamics across vertebrate development.