Latest posts
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August IPD News Roundup
RESEARCH Following the groundbreaking 2014 Nature paper describing the development of a computational method to design multi-component coassembling protein nanoparticles, comes a publication in Protein Science from Baker lab graduate student Jacob Bale and collaborators. Titled “Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression“, the paper reports a…
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July IPD News Roundup
RESEARCH In an article out in Structure, Baker lab postdoc Dr. Hahnbeom Park in collaboration with IPD Assistant Professor Frank DiMaio investigate the origin of protein structure refinement from structural averaging at the residue level. Structure refinement has long been a challenge in the field of protein structure prediction and…
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June IPD News Roundup
RESEARCH A new Science paper is out from Dr. David Baker and IPD collaborator Dr. Tamir Gonen (HHMI Janelia Campus) titled Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces. Graduate student Shane Gonen and Dr. Frank DiMaio describe a new computational approach to design two-dimensional protein arrays with a…
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New Science paper: Designed 2-D protein arrays
A new Science paper is out from IPD faculty Dr. David Baker titled Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces. Read the abstract below and the article at the link: http://www.sciencemag.org/content/348/6241/1365 We describe a general approach to designing two-dimensional (2D) protein arrays mediated by noncovalent protein-protein interfaces. Protein homo-oligomers are…
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IPD Launches First Company Spinout
Seattle, WA Today, we are announcing that Cyrus Biotechnology, has been successfully launched from the UW Institute for Protein Design (IPD) to pursue commercialization of an innovative user friendly software as a service (SaaS) cloud computing solution for distribution of the powerful “Rosetta” protein structure prediction and design algorithms. “Cyrus…
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May IPD News Roundup
The May IPD News Roundup covers a new Science paper from IPD Assistant Prof Frank DiMaio, a KOMO News interview with Translational Investigator Ingrid Swanson Pultz on celiac disease, and much more! At the link.
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New structure solved for hyperthermophilic DNA virus
A new Science paper is out from IPD faculty Dr. Frank DiMaio titled A virus that infects a hyperthermophile encapsidates A-form DNA. Read the abstract below and the article at the link: http://www.sciencemag.org/content/348/6237/914.full.pdf Extremophiles, microorganisms thriving in extreme environmental conditions, must have proteins and nucleic acids that are stable at extremes of…
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One-carbon pathway PNAS paper featured in Nature Chem Bio
The exciting protein design work by IPD researchers and collaborators in PNAS titled Computational protein design enables a novel one-carbon assimilation pathway has been featured in a Nature Chemical Biology News and Views piece. Follow the link to check it out: nchembio.1819
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April IPD News Roundup
April IPD News Roundup is live at this link!
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March IPD News Roundup
The March 2015 IPD news roundup is here! A new publication in PNAS on a completely novel metabolic pathway made via protein design and more. Read about it at the link.