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  • 2018 IPD Newsletter from David Baker

    2018 IPD Newsletter from David Baker

    It was a great year for the Institute for Protein Design and we couldn’t have done all of our amazing work without the support from our donors and contributors! Thank you to everyone who helped us, whether through a donation, collaboration, playing Foldit, or otherwise. We’ve filled the IPD Newsletter…

  • Open Philanthropy awards $11.3 million  to the Institute for Protein Design

    Open Philanthropy awards $11.3 million to the Institute for Protein Design

    The funds will support our technological revolution in protein design and enable the development of a universal flu vaccine. The $11.3 gift is one of the largest made to date by the San Francisco-based philanthropy in support of science. It is also the first to go to UW Medicine. The…

  • SCI-STEM Symposium 2018

    SCI-STEM Symposium 2018

    Update 2018-07-26: The 2018 SCI-STEM Symposium was recently featured in an eLife article. The Institute for Protein Design at the University of Washington held its first ever symposium aimed at providing strategies to address diversity challenges in science, technology, engineering, and math (STEM). The Strategies for Cultivating Inclusion in STEM…

  • De Novo Design of Membrane Proteins

    De Novo Design of Membrane Proteins

    It is now possible to create complex, custom-designed transmembrane proteins from scratch !   Today Baker lab members published in Science  “Accurate computational design of multipass transmembrane proteins” The Abstract reads as follows: The computational design of transmembrane proteins with more than one membrane-spanning region remains a major challenge. We report…

  • David Baker profiled in The New York Times

    David Baker profiled in The New York Times

    At the end of a historic year for protein design, the Baker Lab was honored to be profiled in the New York Times by science writer Carl Zimmer. He writes about the technology, progress, and promise in the field, including the contributions from our wonderful crowdsource participants. Graphic: John Hersey /…

  • A New World of Designed Macrocycles

    A New World of Designed Macrocycles

    Today marks another major step forward for peptide based drug discovery.  IPD researchers report in Science the computational design of a new world of small cyclic peptides, “Macrocycles”,  increasing the number of the known kinds of these molecules by multiple fold.  The conceptual art image below “Illuminating the energy landscape” shows…

  • Synthetic Nucleocapsids Have Arrived

    Synthetic Nucleocapsids Have Arrived

    Published today in Nature, IPD researchers describe the first synthetic protein assemblies — dubbed synthetic nucleocapsids — that encapsulate their own genome and evolve in complex environments. Synthetic nucleocapsids are built to resemble viral capsids and could be used in future to deliver therapeutics to specific cells and tissues. These icosahedral protein…

  • Foldit to Disarm a Fungal Toxin

    Foldit to Disarm a Fungal Toxin

    Foldit alfatoxin project update 7/16/2018 Today, scientists from of the Institute for Protein Design will join Foldit gamers from around the world to help design an enzyme that can neutralize aflatoxin — a cancer-causing toxin produced by certain fungi that are found on agricultural crops such as corn, peanuts, cottonseed, and tree…

  • Designs on New World of Mini-Protein Therapeutics

    Designs on New World of Mini-Protein Therapeutics

    Mark your calendars!  September 27, 2017 is the day the doors opened to whole new world of targeted therapeutics.  The Baker lab and numerous talented collaborators published in Nature that it is now possible to conduct “Massively parallel de novo protein design for targeted therapeutics”.  Three factors make this possible: Rosetta molecular…

  • 2017 IPD Newsletter from David Baker

    2017 IPD Newsletter from David Baker

    It was a great year for the Institute for Protein Design and we couldn’t have done all of our amazing work without the support from our donors and contributors! Thank you to everyone who helped us, whether through a donation, collaboration, playing Foldit, or otherwise. We’ve filled the IPD Newsletter…